Match the main tile as closely as possible. That will let the pretty stone shine, and the contrast with the accent tile will make it stand out pleasingly.

Is the 1x1 tile a border? And the longer copper the accent tile? If 1x1 is a border, I would do some samples of it grouted in the main body colour and in a darker that disappears against the tile.

OK, thanks! That sounds easy :)

Lindsey, the 1x1 is not a border. It will spaced every other tile in a zigzag pattern like in the attached photo. I found this on Houzz. Sorry it's sideways.

Ok, now I get that. What is the copper antique patina scrolly piece posted last in your original post? I was confused, I thought that was the accent tile.

To your original question, I would still say match the body tile :)

I think it would use the same color as the tile for the grout color. I love your design very Tuscan and Mediterranean

Dark colored grout ... bronze colored.

I vote for grout the same color as the tile, allowing your accents to make more of a statement.

Oh I see now--the original photo was stretched, so I thought it was 1x2 or so! Thanks for reposting :)

When using a natural stone always work w a grout color that essentially disappears bc u want the stone to do the talking. Any contrasting grout color will break up the field. Fun w ceramic tile but not so much w natural stone.