As chookchook said in her recommendation about painting, put a drop cloth on the floor. Get a very safe ladder. remove the lightbulbs, and cover the outlets. Turn off the electricity to the chandelier. Then spray it with a mild cleaner (I use one I found at Target that's basically water with vinegar, until it's dripping wet. Start at the bottom and work your way up, so you don't have dirty spray dripping on the bottom of the chandelier.Work your way up and down until the dripping spray is clean. The chandelier may be gorgeous and expensive, but it seems totally out of place in the architecture of the room--more at home in a chalet than a sunny room with a window wall. I would probably try to find a way to get it removed, and sell it to someone who appreciated it better than I.

Medicine cabinets have come along way in recent years. The best option is to get a frameless style and integrate it into a wall of mirror. You can mount sconces thru the mirror on either side of the cabinet. If you have walls on either side of the sink, you can put the cabinets to the side, integrated into mirror again. If you have an open wall in your bath, yo can get an extra tall medicine cabinet to hold loads of stuff. There are loads more on houzz photos. Just search medicine cabinet. Sometimes you have to hunt for the cabinet because they are so well integrated. Robern makes some of the best frameless styles, but there are a ton of others on faucetdirect.com. Many even come with integrated lighting for a very modern look.

Well, for lack of a better idea, since you find it a drafty little space. I'm assuming the draft comes in on the right? Most of the necessities in the area are located of the left side; i.e. vent, thermostat, light switch etc. What I would do I think is caulk up the drafty spots, maybe even add sized poster board wrapped in batting I covered in a gorgeous fuscia with diagonal grosgrain ribbons every which way covered with a heavy velvet to be attached to the area above & below the window. (Of course remove the drapes that are hanging in there). This for the purpose of using it as a pin-it board for notes. Attach a table height board covered in felt to carry across the full width of the little room. Leaving just enough space for a comfortable little antique desk chair. Paint the back wall a bright cobalt blue, paint the ceiling a silvery pearlescent white. Find a way to attach a clip-on task lamp. And stretch a heavy duty enough wire across the top of the opening and complete it with a heavy doubled velvet drape with a drooping valance. Place a swag with fringe & jewels on it to be closed when not in use. Voila intrigue is yours!

Wall sconces are for additional lighting mostly decorative you need ambient light, task light and decorative light in a space the downlights are the best way to get ambient light which the allover light you need then lamps for reading or any task that requires good close lighting and then your sconces